Ovarian activity in crossbred Thai native does during naturally occurring foot-and-mouth disease (FMD) virus infection

Abstract

This study aimed to compare the follicular dynamics in goats during naturally infected with foot-and-mouth disease virus (FMD) subjected to induced ovulations, and after disease recovery, crossbred Thai native does were synchronized with CIDR for 14 days, and then PGF2α and PMSG were administered on the day following CIDR removal. The ovarian activity was determined by transrectal ultrasonography. Clinical signs (fever, anorexia, lameness, and foot lesion) were observed on day 12 post-estrus (day 0, day of expected estrus). The study was carried out for 2 periods: FMD outbreak (day 0–day 21) and FMD recovery (day 63–day 84). Infected does were classified into two groups: (I) does without (n = 5) and (II) does with clinical signs (n = 5). The results showed that during FMD outbreak, the number of follicles/waves and number of follicles > 5 mm in ovulatory follicle wave of group II were lower than those of group I and those of its own group after FMD recovery (P<0.05). Higher in follicular regression rate were found in group II compared to group I in the does with 3 follicular waves during FMD outbreak (P<0.05). Moreover, during FMD outbreak, the does had lower number of follicles > 5 mm and longer day of emergence and day of largest follicles in ovulatory follicle wave than of those after FMD recovery. This observation demonstrated that FMD impaired folliculogenesis in goats, and the ovarian activity could be restored about 1 month after disease recovery.