Please use this identifier to cite or link to this item: http://cmuir.cmu.ac.th/jspui/handle/6653943832/72288
Title: Dietary red macroalgae (Halopithys incurva) improved systemic an mucosal immune and antioxidant parameters and modulated related gene expression in zebrafish (Danio rerio)
Authors: Seyed Hossein Hoseinifar
Zohreh Fazelan
Mahsan Bayani
Morteza Yousefi
Hien Van Doan
Metin Yazici
Authors: Seyed Hossein Hoseinifar
Zohreh Fazelan
Mahsan Bayani
Morteza Yousefi
Hien Van Doan
Metin Yazici
Keywords: Agricultural and Biological Sciences;Environmental Science;Immunology and Microbiology
Issue Date: 1-Apr-2022
Abstract: In the present study, the effects of dietary Halopithys incurva, a red macroalgae species, (0.25, 0.50, 1%) on whole-body serum and skin mucus immune system, antioxidant system and expression of various genes in zebrafish were investigated. At the end of the 8-week study, total protein, total immunoglobulin and lysozyme activities in whole-body serum and skin mucus increased in fish fed H. incurva (P < 0.05). While an increase was observed in superoxide dismutase (SOD), Catalase (CAT) and glutathione peroxidase (GPx) which are antioxidant enzyme activities in whole-body serum and skin mucus, a decrease in malondialdehyde (MDA) levels was detected (P < 0.05). All of the immune-related genes examined, such as Interleukin-1 beta (IL-1β), Tumor necrosis factor-alpha (TNF-α), Interferon-gamma (INF- γ), were upregulated by the addition of 0.5% H. incurva (P < 0.05). While SOD and GPx, which are antioxidant enzyme-related genes, were remarkably upregulated in macroalgae fed fish (P < 0.05), no change was observed in CAT gene expression (P > 0.05). Based on the results of this study, it is considered that the addition of 0.5% H. incurva to the diets of commercially farmed fish will increase their immune and antioxidant defences and may contribute to the aquaculture sector for more sustainability.
URI: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85125872399&origin=inward
http://cmuir.cmu.ac.th/jspui/handle/6653943832/72288
ISSN: 10959947
10504648
Appears in Collections:CMUL: Journal Articles

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