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http://cmuir.cmu.ac.th/jspui/handle/6653943832/71821| Title: | Genomic analysis of group A rotavirus G12P[8] including a new Japanese strain revealed evidence for intergenotypic recombination in VP7 and VP4 genes |
| Authors: | Tung Phan Tomihiko Ide Satoshi Komoto Pattara Khamrin Ngan Thi Kim Pham Shoko Okitsu Koki Taniguchi Shuichi Nishimura Niwat Maneekarn Satoshi Hayakawa Hiroshi Ushijima |
| Authors: | Tung Phan Tomihiko Ide Satoshi Komoto Pattara Khamrin Ngan Thi Kim Pham Shoko Okitsu Koki Taniguchi Shuichi Nishimura Niwat Maneekarn Satoshi Hayakawa Hiroshi Ushijima |
| Keywords: | Agricultural and Biological Sciences;Biochemistry, Genetics and Molecular Biology;Immunology and Microbiology;Medicine |
| Issue Date: | 1-Jan-2021 |
| Abstract: | © 2020 Elsevier B.V. Group A rotavirus is a leading cause of severe acute gastroenteritis worldwide. In this study, the first complete coding sequences of 11 RNA segments of human group A rotavirus G12P[8] in Japan were determined by an unbiased viral metagenomics. Its genomic constellation (VP7-VP4-VP6-VP1-VP2-VP3-NSP1-NSP2-NSP3-NSP4-NSP5 genes) was identified as G12-P[8]-I1-R1-C1-M1-A1-N1-T1-E1-H1. When performing the genetic analysis, we discovered an intergenotypic recombination event in the pig group A rotavirus G12P[8] strain BUW-14-A008. The novel recombination was found between two different genotypes G12 and G3 in the VP7 gene, and P[8] and P[13] in the VP4 gene. |
| URI: | https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85097467714&origin=inward http://cmuir.cmu.ac.th/jspui/handle/6653943832/71821 |
| ISSN: | 15677257 15671348 |
| Appears in Collections: | CMUL: Journal Articles |
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