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Title: Spirulina platensis alleviated the oxidative damage in the gills, liver, and kidney organs of nile tilapia intoxicated with sodium sulphate
Authors: Eman M. Awed
Kadry M. Sadek
Magdy K. Soliman
Riad H. Khalil
Elsayed M. Younis
Abdel Wahab A. Abdel-Warith
Hien Van Doan
Mahmoud A.O. Dawood
Hany M.R. Abdel-Latif
Keywords: Agricultural and Biological Sciences
Issue Date: 1-Jan-2020
Abstract: © 2020 by the authors. Licensee MDPI, Basel, Switzerland. The current study aimed at assessing the recuperative roles of dietary Spirulina platensis on the antioxidation capacity of Nile tilapia (Oreochromis niloticus) exposed to sodium sulphate for eight weeks. In brief, fish were allocated into four groups with three triplicates per group, where a group fed on a commercial basal diet served as control, a group was intoxicated with sodium sulphate (SS) 5.8 mg/L, another group was fed a diet supplemented with 1% S. platensis (SP), and the last group was fed 1% SP and concomitantly intoxicated with 5.8 mg/L sodium sulphate (SP/SS). Tissue antioxidative indices of each fish were measured as follows: glutathione peroxidase (GSH-Px) activity in muscles, catalase (CAT) and superoxide dismutase (SOD) activities in gills, and total antioxidant capacity (T-AOC) in the liver and kidney. Moreover, the expression of hepatic SOD, GSH-Px, and glutathione-S-transferase (GST) genes was also determined. It was found that tissue CAT, SOD, and GSH-Px activities as well as the T-AOC levels were significantly decreased in the SS group (p < 0.05). Moreover, there was a significant downregulation of hepatic SOD, GSH-Px, and GST genes in SS-exposed fish (p < 0.05). Interestingly, simultaneous dietary supplementation with SP provided a marked attenuation of the tissue antioxidative parameters when compared with the SS and control groups. To conclude, the present study exemplifies that dietary SP supplementation could be a beneficial abrogation of SS-induced tissue oxidative stress in the exposed fish.
ISSN: 20762615
Appears in Collections:CMUL: Journal Articles

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