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http://cmuir.cmu.ac.th/jspui/handle/6653943832/71030| Title: | Larval and gut enzyme toxicity of n-hexane extract Epaltes pygmaea DC. against the arthropod vectors and its non-toxicity against aquatic predator |
| Authors: | Kesavan Amala Raja Ganesan Seengodan Karthi Sengottayan Senthil-Nathan Muthiah Chellappandian Patcharin Krutmunag Narayanaswamy Radhakrishnan Faruq Mohammad Athirstam Ponsankar Prabhakaran Vasantha-Srinivasan |
| Authors: | Kesavan Amala Raja Ganesan Seengodan Karthi Sengottayan Senthil-Nathan Muthiah Chellappandian Patcharin Krutmunag Narayanaswamy Radhakrishnan Faruq Mohammad Athirstam Ponsankar Prabhakaran Vasantha-Srinivasan |
| Keywords: | Pharmacology, Toxicology and Pharmaceutics |
| Issue Date: | 1-Jan-2020 |
| Abstract: | © 2020, © 2020 Informa UK Limited, trading as Taylor & Francis Group. The crude n-hexane extracts Epaltes pygmaea (NH-Epx) displayed a steady larval toxicity against Culex quinquefasciatus and Aedes aegypti at the maximum dosage of 125 ppm. The level of α- and β carboxylesterase activity was downregulated to the sub-lethal dosage of NH-EPx (75 ppm) in both vectors. The level of GST and CYP450 gets upregulated. The LC50 and the LC90 of NH-EPx were observed at 63 and 117 ppm and 73 and 120 ppm dosage against both the vectors, respectively. NH-EPx treatment showed morphological alterations in the gut tissues. The non-target screening recommends that NH-EPx is safe against aquatic predator. |
| URI: | https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85083547135&origin=inward http://cmuir.cmu.ac.th/jspui/handle/6653943832/71030 |
| ISSN: | 15569551 15569543 |
| Appears in Collections: | CMUL: Journal Articles |
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