Please use this identifier to cite or link to this item: http://cmuir.cmu.ac.th/jspui/handle/6653943832/70895
Title: Plasma volume treated with double filtration plasmapheresis and outcomes of acute antibody-mediated rejection in kidney transplant recipients: A retrospective cohort study
Authors: Kajohnsak Noppakun
Thanapat Kittipanyaworakun
Chidchanok Ruengorn
Surachet Vongsanim
Anchalee Saikam
Nikhom Khamlueang
Keywords: Medicine
Issue Date: 1-Jan-2020
Abstract: © 2020 International Society for Apheresis, Japanese Society for Apheresis, and Japanese Society for Dialysis Therapy A retrospective cohort study was conducted to evaluate the association between the plasma volume treated by double filtration plasmapheresis and allograft outcomes for the treatment of acute antibody-mediated rejection in kidney transplant recipients. Patients were divided into two groups: group 1, plasma volume treated between 1 and <1.3 total plasma volume and group 2, plasma volume treated ≥1.3 total plasma volume. Primary outcome was ≥50% reduction of serum creatinine rising from baseline value at 1 month. A total of 32 courses (146 sessions) of double filtration plasmapheresis were performed; 17 and 15 courses in group 1 and group 2, respectively. Primary outcome occurred in 41% of group 1 and 40% of group 2 (adjusted risk ratio 1.15 [95%CI, 0.48-2.76]). Graft loss at 1 year did not differ between the two groups (adjusted hazard ratio 0.65 [95%CI, 0.23-1.87]). Infection tendency seemed to be higher in group 2 (40% vs 18%, P =.243).
URI: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85089448647&origin=inward
http://cmuir.cmu.ac.th/jspui/handle/6653943832/70895
ISSN: 17449987
17449979
Appears in Collections:CMUL: Journal Articles

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