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Title: Commercial Copper-Catalyzed Aerobic Oxidative Synthesis of Quinazolinones from 2-Aminobenzamide and Methanol
Authors: Sutthichat Kerdphon
Patthadon Sanghong
Jaruwan Chatwichien
Vachira Choommongkol
Puracheth Rithchumpon
Thishana Singh
Puttinan Meepowpan
Keywords: Chemistry
Issue Date: 14-May-2020
Abstract: © 2020 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim The focus of this study was the development of a new synthetic method for quinazolinones based on the principles of Green Chemistry. Quinazolinones were synthesized from 2-aminobenzamide using methanol as both the C1 source and a green solvent in the presence of base Cs2CO3. Additionally, a commercially available, economical copper complex was used as a catalyst in the reaction. The desired products were achieved in moderate to high yield with up to 99 % isolated yield.
ISSN: 10990690
Appears in Collections:CMUL: Journal Articles

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