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http://cmuir.cmu.ac.th/jspui/handle/6653943832/67340| Title: | Synthesis of 6/8-Methyl-2-(piperidin-1-yl)quinoline-3-carbaldehydes: A Facile CTAB Catalyzed Protocol |
| Authors: | Rubina Munir Muhammad Makshoof Atha Muhammad Zia-ur-Rehman Noman Javid |
| Authors: | Rubina Munir Muhammad Makshoof Atha Muhammad Zia-ur-Rehman Noman Javid |
| Keywords: | quinoline;nucleophilic aromatic substitution;phase transfer catalyst;CTAB;piperidine |
| Issue Date: | 2020 |
| Publisher: | Science Faculty of Chiang Mai University |
| Citation: | Chiang Mai Journal of Science 47, 1 (January 2020), 175-180 |
| Abstract: | An efficient method for nucleophilic aromatic substitution of 2-chloroquinoline-3-carbaldehydes is described for the synthesis of 6/8-methyl-2-(piperidin-1-yl)quinoline-3-carbaldehydes. The protocol involves the effective use of phase transfer catalyst CTAB in combination with polyethyleneglycol-400 to obtain the desired products in less reaction time. The newly developed method is found superior to the previously reported methods due to easy work up and excellent yields. |
| URI: | http://epg.science.cmu.ac.th/ejournal/dl.php?journal_id=10585 http://cmuir.cmu.ac.th/jspui/handle/6653943832/67340 |
| ISSN: | 0125-2526 |
| Appears in Collections: | CMUL: Journal Articles |
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