Bacterial isolates and antimicrobial susceptibility in dogs with urinary tract infection in Thailand: a retrospective study between 2013-2017

Abstract

Urinary tract infections (UTIs) are one of the most common diseases and are required antimicrobial prescription in small animal practice. Moreover, the proper antimicrobial drug use is crucial for successfully treating UTIs in dogs. Although, several studies have reported the use of antimicrobials in dogs with UTIs, however, the report in tropical countries are lacking. The objectives of this study were to identify bacterial pathogens and to analyze antimicrobial susceptibility in dogs with UTIs. Dogs with suspected UTIs admitted at Veterinary Teaching Hospital (VTH), Khon Kaen University (KKU) between 2013- 2017 were included in the present study. The urine samples were collected using either cystocentesis or urinary catheterization. All urine samples were later submitted to the Veterinary Clinical Diagnostic Laboratory (VCDL) within 30 min. The samples were performed for bacterial identification and drug susceptibility tests. The most common bacterial isolates were Staphylococcus intermedius (33.58%, n = 46), Proteus mirabilis (27.01%, n = 37) and Escherichia coli (19.71%, n = 27), respectively. Interestingly, amoxycillin-clavulanic acid was the most drug susceptibility to all isolated bacteria in the present study ranging from 66-86%. However, when focusing on the most common bacterial isolates in the present study, 86.36% of Staphylococcus intermedius, 86.12% of Proteus mirabilis and 77.77% of E. coli were susceptible to amoxicillin-clavulanic acid. In conclusion, emerging multi-drug resistance is of concern worldwide, antibiotics should be decided depending on culture and susceptibility test.