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Title: A comparison of perioperative and early post-operative complications with laparoscopic radical cystectomy with open radical cystectomy in bladder cancer
Other Titles: การเปรียบเทียบภาวะแทรกซ้อนในระยะแรกของการผ่าตัดกระเพาะปัสสาวะแบบผ่าตัดผ่าน ทางกล่องและผ่าตัดเปิด
Authors: Taweedate Muenkhamsee
Supon Sriplakich
Issue Date: 2016
Publisher: Faculty of Medicine, Chiang Mai University
Abstract: Objectives To compare perioperative complications and early post-operative complications occurring within 90 days following laparoscopic radical cystectomy (LRC) and open radical cystectomy (ORC). Methods This ambispective cohort study included 175 patients who underwent radical cystectomy (100 LRC and 75 ORC) between January 2006 and June 2016. Primary outcomes evaluated complications occurring within 90 days of the operation as defi ned by the modifi ed Clavien-Dindo system. Secondary outcomes evaluated included operative duration, blood loss, blood transfusion, post-operative pain score, post-operative opioid usage, and length of hospital stay. Primary and secondary outcomes were compared between the two groups. Results Comparable rates of Clavien-Dindo grade 1-5 complications were observed in both groups and no differences were observed in intraoperative complications. Mean operative times were longer in the LRC group (p<0.05). Mean blood loss and total blood transfusion was lower in the LRC group (p<0.05) as were mean pain scores and total opioid usage (p<0.05). Mean length of hospital stay was the same in both groups. Conclusion LRC patients have less blood loss, lower blood transfusion rate, and decreased postoperative pain and opioid usage compared to ORC patients. Operative time is shorter for ORC patients. There are no statistically signifi cant differences in post-operative complication rates between LRC and ORC. A limitation of this study was the preponderance of female patients.
Description: Chiang Mai Medical Journal (Formerly Chiang Mai Medical Bulletin) is an official journal of the Faculty of Medicine, Chiang Mai University. It accepts original papers on clinical and experimental research that are pertinent in the biomedical sciences. The Journal is published 4 issues/year (i.e., Mar, Jun, Sep, and Dec).
ISSN: 0125-5983
Appears in Collections:CMUL: Journal Articles

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