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Title: Immunohistochemistry of the chondroitin sulfate epitope in various normal human tissues of fresh cadavers
Other Titles: ภาวะลิ่มเลือดในหลอดเลือดดำส่วนลึกและลิ่มเลือดอุดตันในหลอดเลือดแดงปอดในผู้ป่วย ศัลยกรรมประสาท
Authors: Opat Keerewatcharaporn
Siriwan Ongchai
Sikrai Loawatnapong
Lamaiporn Peerapapong
Peeraphan Pothacharoen
Sirinda Aungsuchawan
Issue Date: 2016
Publisher: Faculty of Medicine, Chiang Mai University
Abstract: Objective The purpose of this study was to reveal the expression trend of the WF6 epitope in various normal human tissues. Methods Ten types of tissue samples from the brain, adipose, skeletal muscle, tendon, liver, cartilage, cardiac muscle, lung, nerve, and, skin were used in this study. They were obtained from fi ve fresh cadavers aged 20-70 years and stained with H and E for their general morphology. In addition, expression of the WF6 epitope was examined using immuno localization. Results The results demonstrated that WF6 epitope expression in the ten tissues can be categorized into three levels, with the highest being found in the brain, skeletal muscle, cartilage, cardiac muscle and skin tissues. A moderate level was found in the adipose, liver, lung and nerve tissues, and the lowest level was found in the tendon tissue. Conclusion The WF6 epitope was expressed at different levels in all of the various normal tissues. This refl ects the important role of this biomolecule for all cells, which may be benefi cial for further study in pathological tissues.
Description: Chiang Mai Medical Journal (Formerly Chiang Mai Medical Bulletin) is an official journal of the Faculty of Medicine, Chiang Mai University. It accepts original papers on clinical and experimental research that are pertinent in the biomedical sciences. The Journal is published 4 issues/year (i.e., Mar, Jun, Sep, and Dec).
ISSN: 0125-5983
Appears in Collections:CMUL: Journal Articles

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