Original article : Patients with ocular manifestations in congenital craniofacial anomalies at Chiang Mai University Hospital

Abstract

Objective To report on patients with ocular manifestations in congenital craniofacial anomalies at Chiang Mai University Hospital. Material and methods Patients were examine and diagnosed with congenital craniofacial anomalies retrospectively at Chiang Mai University Hospital between 1st June 2013 and 28th February 2014. Results Of 55 patients with congenital craniofacial anomalies, 18 (32.7%) had ocular abnormalities, 1 (1.82%) had craniosynostosis in Crouzon’s syndrome, 54 (98.2%) had clefting syndrome, 36 (65.45%) had cleft lip and palate, 15 (27.28%) had mandibulofacial deformitiesand, and 3 (5.45%) had oblique facial clefts, as shown in Table 1. The mean age of the patients was 5.689 years (range 1 month-19 years), of which 38.2% (n=21) were female and 61.8% (n=34) male. Fifty fi ve percent of the patients were below the age of 5 years and 23.6% below the age of 10. The various ocular abnormalities found in this study are listed in Table 2. A total of 21 ocular defects were identifi ed in 18 patients. Abnormalities of the eyelid were the most common, accounting for 28.5% of the total defects (6/21), which included ectropion, lid colobomas, euryblepharon and lagopthalmos. The second most common abnormality was equally strabismus and refractive errors, 4/21(19.0%), followed by nasolacrimal duct obstruction, 3/21(14.3%), limbal dermoid, 1/21(4.8%), preauricular skin tag, 1/21(4.8%), enlarged cupping, 1/21(4.8%), and retinal atrophy, 1/21(4.8%). Conclusion Common ocular manifestations in patients with congenital craniofacial anomalies included eyelid abnormalities at Chiang Mai University Hospital.