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Title: Phytochemical studies on Stemona plants: Isolation of stemofoline alkaloids
Authors: Thanapat Sastraruji
Araya Jatisatienr
Stephen G. Pyne
Alison T. Ung
Wilford Lie
Morwenna C. Williams
Keywords: Biochemistry, Genetics and Molecular Biology
Pharmacology, Toxicology and Pharmaceutics
Issue Date: 1-Dec-2005
Abstract: Six new stemofoline alkaloids, (2′A)-hydroxystemofoline (5), (3′R)-stemofolenol (6), (3′S)-stemofolenol (7), 1′,2′- didehydrostemofoline-AT-oxide (8), the first C19stemofoline alkaloid, methylstemofoline (9), and the first glycosidated Stemona alkaloid, stemofolinoside (10), and three known alkaloids, (2′S)-hydroxystemofoline (2), (HZ)-1′,2′-didehydrostemofoline (3), and (11E)-1′, 2′-didehydrostemofoline (4), have been isolated from a root extract of an unidentified Stemona species. The structure and relative configuration of these new alkaloids have been determined by spectral data interpretation and from semisynthetic studies. © 2005 American Chemical Society and American Society of Pharmacognosy.
ISSN: 01633864
Appears in Collections:CMUL: Journal Articles

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