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http://cmuir.cmu.ac.th/jspui/handle/6653943832/61512| Title: | The influence of pH on the G-quadruplex binding selectivity of perylene derivatives |
| Authors: | Wirote Tuntiwechapikul Thanachai Taka Mathilde Béthencourt Luksana Makonkawkeyoon T. Randall Lee |
| Authors: | Wirote Tuntiwechapikul Thanachai Taka Mathilde Béthencourt Luksana Makonkawkeyoon T. Randall Lee |
| Keywords: | Biochemistry, Genetics and Molecular Biology;Chemistry;Pharmacology, Toxicology and Pharmaceutics |
| Issue Date: | 1-Aug-2006 |
| Abstract: | Three new perylene derivatives with branched ionizable side chains were synthesized, and their G-quadruplex binding specificities were compared by spectroscopic and electrophoretic analysis with two well-studied G-quadruplex ligands: PIPER and TmPyP4. The value of pH and consequent charge formation and self-aggregation of these perylene derivatives influences not only the type of G-quadruplex formation, but also the G-quadruplex binding selectivity. © 2006 Elsevier Ltd. All rights reserved. |
| URI: | https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=33745141952&origin=inward http://cmuir.cmu.ac.th/jspui/handle/6653943832/61512 |
| ISSN: | 0960894X |
| Appears in Collections: | CMUL: Journal Articles |
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