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Title: Cryptococcal immune reconstitution inflammatory syndrome after antiretroviral therapy in AIDS patients with cryptococcal meningitis: A prospective multicenter study
Authors: Somnuek Sungkanuparph
Scott G. Filler
Ploenchan Chetchotisakd
Peter G. Pappas
Tracy L. Nolen
Weerawat Manosuthi
Thanomsak Anekthananon
Michèle I. Morris
Khuanchai Supparatpinyo
Heather Kopetskie
Amy S. Kendrick
Philip C. Johnson
Jack D. Sobel
Robert A. Larsen
Keywords: Medicine
Issue Date: 15-Sep-2009
Abstract: A prospective multicenter study of cryptococcal immune reconstitution inflammatory syndrome (IRIS) was conducted as a substudy of the Bacteriology and Mycology Study Group 3-01. Of 101 AIDS patients with cryptococcal meningitis who received highly active antiretroviral therapy (HAART), 13 experienced cryptococcal IRIS. No association between the timing of HAART initiation and the diagnosis of IRIS was identified. Increased baseline serum cryptococcal antigen (CrAg) titer was a risk factor for cryptococcal IRIS. © 2009 by the Infectious Diseases Society of America. All rights reserved.
ISSN: 10584838
Appears in Collections:CMUL: Journal Articles

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