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Title: Nocardia beijingensis pericarditis presenting with cardiac tamponade: A case report
Authors: Nattinee Laksananun
Parichat Salee
Quanhathai Kaewpoowat
Keywords: Medicine
Issue Date: 1-Apr-2018
Abstract: © 2017, © The Author(s) 2017. We report the first case of Nocardia beijingensis pericarditis in a 32-year-old HIV-infected patient. He presented with cardiac tamponade after failing to respond to treatment for smear-negative pulmonary and pericardial tuberculosis (TB). The pericardial fluid was examined several times before it eventually revealed filamentous branching organisms in Gram and modified acid-fast bacilli stain. The culture grew Nocardia spp. and was identified by 16s rRNA sequencing as N. beijingensis. Eight previously reported cases of Nocardia pericarditis in HIV-infected patients were caused by Nocardia asteroides. All patients had low CD4 cell count (range: 17–239 cells/mm3) and 50% of patients were treated for tuberculous pericarditis prior to making the correct diagnosis of Nocardia pericarditis. This report revisits the issue of nocardiosis as a great TB mimicker. It should always be considered in the differential diagnosis among HIV-infected patients suspected of having pericardial TB that is failing treatment.
ISSN: 17581052
Appears in Collections:CMUL: Journal Articles

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