Please use this identifier to cite or link to this item:
http://cmuir.cmu.ac.th/jspui/handle/6653943832/57687
Title: | Development of a multidimensional assessment tool for uraemic pruritus: Uraemic Pruritus in Dialysis Patients (UP-Dial) |
Authors: | S. Nochaiwong C. Ruengorn R. Awiphan S. Panyathong K. Noppakun W. Chongruksut S. Chiewchanvit |
Authors: | S. Nochaiwong C. Ruengorn R. Awiphan S. Panyathong K. Noppakun W. Chongruksut S. Chiewchanvit |
Keywords: | Medicine |
Issue Date: | 1-Jun-2017 |
Abstract: | © 2017 British Association of Dermatologists Background: Dialysis patients with uraemic pruritus (UP) have significantly impaired quality of life. To assess the therapeutic effect of UP treatments, a well-validated comprehensive and multidimensional instrument needed to be established. Objectives: To develop and validate a multidimensional scale assessing UP in patients on dialysis: the Uraemic Pruritus in Dialysis Patients (UP-Dial). Methods: The development and validation of the UP-Dial instrument were conducted in four phases: (i) item generation, (ii) development of a pilot questionnaire, (iii) refinement of the questionnaire with patient recruitment and (iv) psychometric validation. Participants completed the UP-Dial, the visual analogue scale (VAS) of UP, the Dermatology Life Quality Index (DLQI), the Kidney Disease Quality of Life-36 (KDQOL-36), the Pittsburgh Sleep Quality Index (PSQI) and the Beck Depression Inventory (BDI) between 15 May 2012 and 30 November 2015. Results: The 27-item pilot UP-Dial was generated, with 168 participants completing the pilot scale. After factor analysis was performed, the final 14-item UP-Dial encompassed three domains: signs and symptoms, psychosocial, and sleep. Face and content validity were satisfied through the item generation process and expert review. Psychometric analysis demonstrated that the UP-Dial had good convergent and discriminant validity. The UP-Dial was significantly correlated [Spearman rank coefficient, 95% confidence interval (CI)] with the VAS-UP (0·76, 0·69–0·83), DLQI (0·78, 0·71–0·85), KDQOL-36 (−0·86, −0·91 to −0·81), PSQI (0·85, 0·80–0·89) and BDI (0·70, 0·61–0·79). The UP-Dial revealed excellent internal consistency (Cronbach's α 0·90, 95% CI 0·87–0·92) and reproducibility (intraclass correlation 0·95, 95% CI 0·90–0·98). Conclusions: The UP-Dial is valid and reliable for assessing UP among patients on dialysis. Future research should focus on the cross-cultural adaptation and translation of the scale to other languages. |
URI: | https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85018977706&origin=inward http://cmuir.cmu.ac.th/jspui/handle/6653943832/57687 |
ISSN: | 13652133 00070963 |
Appears in Collections: | CMUL: Journal Articles |
Files in This Item:
There are no files associated with this item.
Items in CMUIR are protected by copyright, with all rights reserved, unless otherwise indicated.