Salivirus infection in children with diarrhea, Thailand

Abstract

© 2017, Springer-Verlag Wien. A new member of the Picornaviridae family named salivirus, and also known as klassevirus, was identified recently from the feces of children with gastroenteritis. At present, it remains unclear whether salivirus is associated with gastroenteritis in humans and epidemiological data are very limited. To investigate the prevalence of salivirus in Thailand, we performed molecular screening of fecal samples from children hospitalized with acute gastroenteritis in Chiang Mai, Thailand during 2015-2016 through the application of RT-nested PCR. Salivirus was detected in 1 out of 229 (0.44%) fecal samples tested and it belonged to genotype A1, based on nucleotide sequences of the 5’UTR, VP1, and 3D regions. This is the first report of salivirus infection in young children with acute diarrhea in Thailand.