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Title: A convenient synthesis of 4-arylidene-2-phenyl-5(4H)-oxazolones under solvent-assisted grinding
Authors: Mookda Pattarawarapan
Subin Jaita
Wong Phakhodee
Keywords: Biochemistry, Genetics and Molecular Biology
Pharmacology, Toxicology and Pharmaceutics
Issue Date: 1-Jan-2016
Abstract: © 2016 Elsevier Ltd A facile and effective approach for the synthesis of 4-arylidene-2-phenyl-5(4H)-oxazolones has been developed. Under solvent-assisted grinding in the presence of 2,4,6-trichloro-1,3,5-triazine, catalytic triphenylphosphine, and sodium carbonate, dehydration–condensation of hippuric acid with aromatic aldehydes proceeded rapidly within minutes at room temperature to afford the products in good to excellent yields.
ISSN: 18733581
Appears in Collections:CMUL: Journal Articles

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