Please use this identifier to cite or link to this item: http://cmuir.cmu.ac.th/jspui/handle/6653943832/55223
Title: Is salivary gland function altered in noninsulin-dependent diabetes mellitus and obesity-insulin resistance?
Authors: Jitjiroj Ittichaicharoen
Nipon Chattipakorn
Siriporn C. Chattipakorn
Keywords: Biochemistry, Genetics and Molecular Biology
Dentistry
Medicine
Issue Date: 1-Apr-2016
Abstract: © 2016 Elsevier Ltd. All rights reserved. Salivary gland dysfunction in several systemic diseases has been shown to decrease the quality of life in patients. In non-insulin dependent diabetes mellitus (NIDDM), inadequate salivary gland function has been evidenced to closely associate with this abnormal glycemic control condition. Although several studies demonstrated that NIDDM has a positive correlation with impaired salivary gland function, including decreased salivary flow rate, some studies demonstrated contradictory findings. Moreover, the changes of the salivary gland function in pre-diabetic stage known as insulin resistance are still unclear. The aim of this review is to comprehensively summarize the current evidence from in vitro, in vivo and clinical studies regarding the relationship between NIDDM and salivary gland function, as well as the correlation between obesity and salivary gland function. Consistent findings as well as controversial reports and the mechanistic insights regarding the effect of NIDDM and obesity-insulin resistance on salivary gland function are also presented and discussed.
URI: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84954449523&origin=inward
http://cmuir.cmu.ac.th/jspui/handle/6653943832/55223
ISSN: 18791506
00039969
Appears in Collections:CMUL: Journal Articles

Files in This Item:
There are no files associated with this item.


Items in CMUIR are protected by copyright, with all rights reserved, unless otherwise indicated.