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|Title:||A new cytotoxic clerodane diterpene from casearia graveolens twigs|
|Keywords:||Agricultural and Biological Sciences;Medicine;Pharmacology, Toxicology and Pharmaceutics|
|Abstract:||The first phytochemical investigation of Casearia graveolens twigs led to the isolation and identification of a new clerodane diterpene, caseariagraveolin (1), together with six known compounds (2-7). Their structures were elucidated by intensive analysis of their spectroscopic data. Compound 1 showed strong cytotoxicity against oral cavity and breast cancer cell lines with IC50 values of 2.48 and 6.63 ìM, respectively.|
|Appears in Collections:||CMUL: Journal Articles|
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