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http://cmuir.cmu.ac.th/jspui/handle/6653943832/54095| Title: | A convenient one-pot synthesis of ketone cyanohydrin esters in aqueous media |
| Authors: | Sirawit Wet-Osot Mookda Pattarawarapan Wong Phakhodee |
| Authors: | Sirawit Wet-Osot Mookda Pattarawarapan Wong Phakhodee |
| Keywords: | Biochemistry, Genetics and Molecular Biology;Chemistry;Pharmacology, Toxicology and Pharmaceutics |
| Issue Date: | 30-Dec-2015 |
| Abstract: | © 2015 Elsevier Ltd. All rights reserved. A convenient one-pot, two-step procedure for the synthesis of ketone cyanohydrin esters in aqueous media is reported using N-acylbenzotriazoles as the acylating agents. In saturated aqueous sodium bicarbonate containing a catalytic amount of tetrabutylammonium bromide, the reaction of ketones with potassium cyanide and N-acylbenzotriazoles proceeded readily at room temperature to provide the corresponding O-acyl cyanohydrin derivatives in good to excellent yields. |
| URI: | https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84949106013&origin=inward http://cmuir.cmu.ac.th/jspui/handle/6653943832/54095 |
| ISSN: | 18733581 00404039 |
| Appears in Collections: | CMUL: Journal Articles |
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