Please use this identifier to cite or link to this item: http://cmuir.cmu.ac.th/jspui/handle/6653943832/51453
Title: Physico-chemical properties of cationic niosomes loaded with fraction of rice (Oryza sativa) bran extract
Authors: Aranya Manosroi
Warintorn Ruksiriwanich
Masahiko Abe
Hideki Sakai
Kenichi Aburai
Worapaka Manosroi
Jiradej Manosroi
Keywords: Chemical Engineering
Chemistry
Engineering
Materials Science
Physics and Astronomy
Issue Date: 1-Sep-2012
Abstract: The aim of this study was to investigate the physico-chemical properties of cationic niosomes (Tween61/cholesterol/CTAB) loaded with fraction No. 3 of Oryza sativa bran extract (OSF3) at 0.1, 0.5, 1.0 and 2.0% (w/v), respectively, before and after ultra-centrifugation. More white milky translucent appearance of the niosomes was observed at the higher loaded amount of OSF3. The entrapment efficiency of 0.5% OSF3 in niosomes was 86.22plusmn;1-43%. The sizes of the niosomes were slightly increased (120-220 nm) and the zeta potential values were decreased from 80 to the range of 40-60 mV after loaded with OSF3. All niosomes both blank and loaded with OSF3 were in the uni-lamellar structures determined by FF-TEM and SAXS. The transitions temperature (T c) of niosomes significant increased from 75 to 80 °C when loaded with OSF3 at 0.1 and 0.5%. Moreover, blank niosomes showed the highest microviscosity with the most rigid membrane at 25 °C, followed by the niosomes loaded with 0.1, 0.5, 1.0 and 2.0% of OSF3, respectively. The fluorescence polarizations of all niosomal formulations indicated the sharp descending phases at about 40 and 70 °C. After ultra-centrifugation to eliminate the non-loaded negatively charged OSF3, the increased vesicular sizes and zeta potential values of the blank, loaded niosomes with 0.1 and 0.5% OSF3 were observed. All niosomal formulations gave the same transition temperatures at about 71 °C and the same microviscosities at 25 °C. The results from this study can be applied for the niosomal formulation development of the rice bran semi-purified fraction for anti-hair loss products. Copyright © 2012 American Scientific Publishers All rights reserved.
URI: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84866107760&origin=inward
http://cmuir.cmu.ac.th/jspui/handle/6653943832/51453
ISSN: 15334899
15334880
Appears in Collections:CMUL: Journal Articles

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