Please use this identifier to cite or link to this item:
Full metadata record
DC FieldValueLanguage
dc.contributor.authorAksara Thongprachumen_US
dc.contributor.authorPattara Khamrinen_US
dc.contributor.authorDinh Nguyen Tranen_US
dc.contributor.authorShoko Okitsuen_US
dc.contributor.authorMasashi Mizuguchien_US
dc.contributor.authorSatoshi Hayakawaen_US
dc.contributor.authorNiwat Maneekarnen_US
dc.contributor.authorHiroshi Ushijimaen_US
dc.description.abstractBackground: The efficiency of a commercial immunochromatography kit (IP-NoV) was evaluated for rapid detection of norovirus in Japanese fecal specimens and its sensitivity and specificity were compared with two other commercial kits. Methods: A total of 70 samples collected from children who suffered from acute gastroenteritis in 2009-2010 were tested for norovirus by three different immunochromatography kits. RT-PCR was employed as the gold standard method. Results: The sensitivity of IP-NoV, QuickEx-Norovirus, and QuickNavi-Norovirus kits were 85.2%, 63.9%, and 55.7%, respectively. The IP-NoV kit could detect various genotypes of norovirus with higher efficiency as compared to QuickEx-Norovirus and QuickNavi-Norovirus kits. In addition, the phylogenetic analysis revealed that the majority of noroviruses circulating in Japan during 2009-2010 belonged to GII/4 variant 2006b and 2008a, which were responsible for the outbreaks worldwide. Conclusions: The findings indicated that the IC kits could be used as an alternative method for direct detection of norovirus in clinical specimens covering a wide range of norovirus genotypes circulating in Japan.en_US
dc.subjectBiochemistry, Genetics and Molecular Biologyen_US
dc.titleEvaluation and comparison of the efficiency of immunochromatography methods for norovirus detectionen_US
article.title.sourcetitleClinical Laboratoryen_US
article.volume58en_US of Tokyoen_US Mai Universityen_US University School of Medicineen_US
Appears in Collections:CMUL: Journal Articles

Files in This Item:
There are no files associated with this item.

Items in CMUIR are protected by copyright, with all rights reserved, unless otherwise indicated.