Oblongolides from the endophytic fungus Phomopsis sp. BCC 9789

Please use this identifier to cite or link to this item: http://cmuir.cmu.ac.th/jspui/handle/6653943832/50601

Title:	Oblongolides from the endophytic fungus Phomopsis sp. BCC 9789
Authors:	Taridaporn Bunyapaiboonsri Seangaroon Yoiprommarat Prasert Srikitikulchai Kitlada Srichomthong Saisamorn Lumyong
Authors:	Taridaporn Bunyapaiboonsri Seangaroon Yoiprommarat Prasert Srikitikulchai Kitlada Srichomthong Saisamorn Lumyong
Keywords:	Biochemistry, Genetics and Molecular Biology;Chemistry;Medicine;Pharmacology, Toxicology and Pharmaceutics
Issue Date:	22-Jan-2010
Abstract:	Six new oblongolides, W1, W2, X, Y, and Z (1-3, 6, 7) and 2-deoxy-4α-hydroxyoblongolide X (4), and the known compounds oblongolide (8), oblongolides T, C, and Q (5, 9, 10), and (-)-5-methylmellein were isolated from the endophytic fungus Phomopsis sp. BCC 9789. Compound 7 showed anti-HSV-1 activity (IC50 ) 14 μM) and cytotoxic activities against KB, BC, NCI-H187, and nonmalignant (Vero) cell lines with respective IC50 values of 37, 26, 32, and 60 μM. Cytotoxic activity against the BC cell line was also observed for compound 6, with an IC50 value of 48 μM. © 2010 American Chemical Society and American Society of Pharmacognosy.
URI:	https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=76049090657&origin=inward http://cmuir.cmu.ac.th/jspui/handle/6653943832/50601
ISSN:	01633864
Appears in Collections:	CMUL: Journal Articles

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