Please use this identifier to cite or link to this item: http://cmuir.cmu.ac.th/jspui/handle/6653943832/50584
Title: Genetic evidence supports linguistic affinity of Mlabri - a hunter-gatherer group in Thailand
Authors: Shuhua Xu
Daoroong Kangwanpong
Mark Seielstad
Metawee Srikummool
Jatupol Kampuansai
Li Jin
Keywords: Biochemistry, Genetics and Molecular Biology
Medicine
Issue Date: 19-Mar-2010
Abstract: Background: The Mlabri are a group of nomadic hunter-gatherers inhabiting the rural highlands of Thailand. Little is known about the origins of the Mlabri and linguistic evidence suggests that the present-day Mlabri language most likely arose from Tin, a Khmuic language in the Austro-Asiatic language family. This study aims to examine whether the genetic affinity of the Mlabri is consistent with this linguistic relationship, and to further explore the origins of this enigmatic population.Results: We conducted a genome-wide analysis of genetic variation using more than fifty thousand single nucleotide polymorphisms (SNPs) typed in thirteen population samples from Thailand, including the Mlabri, Htin and neighboring populations of the Northern Highlands, speaking Austro-Asiatic, Tai-Kadai and Hmong-Mien languages. The Mlabri population showed higher LD and lower haplotype diversity when compared with its neighboring populations. Both model-free and Bayesian model-based clustering analyses indicated a close genetic relationship between the Mlabri and the Htin, a group speaking a Tin language.Conclusion: Our results strongly suggested that the Mlabri share more recent common ancestry with the Htin. We thus provided, to our knowledge, the first genetic evidence that supports the linguistic affinity of Mlabri, and this association between linguistic and genetic classifications could reflect the same past population processes. © 2010 Xu et al; licensee BioMed Central Ltd.
URI: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=77952274210&origin=inward
http://cmuir.cmu.ac.th/jspui/handle/6653943832/50584
ISSN: 14712156
Appears in Collections:CMUL: Journal Articles

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