การตอบสนองระยะเฉียบพลันระหว่างการออกกำลังกายแบบช่วงและแบบต่อเนื่องที่ระดับความหนักปานกลางต่อภาวะออกซิเดทีฟสเตรสในอาสาสมัครเพศชายที่มีสุขภาพดี

Abstract

This study aimed to evaluate the immediate effect on nitric oxide (NO) and other oxidative stress parameters (malondialdehyde, MDA and glutathione, GSH) from moderate-intensity interval exercise (MIIE) compared with moderate-intensity continuous exercise (MICE). This study was performed in 14 healthy sedentary males aged between 18 and 23 years with a mean age of 20.21± 1.47 years. All of the participants were required to take MICE randomly at 60% (21.15±2.39 ml.min 1 .kg-1 ) of maximal oxygen consumption (VO2max) (35.24 ± 3.99 ml.min-1 .kg-1 ) for 30 mins, and MIIE in three cycles of between low- and moderate-intensity at 40% (14.09 ± 1.59 ml.min-1 .kg-1 ) and 70% (24.67±2.79 ml.min-1 .kg-1 ) of VO2max, respectively, for 37 mins with stationary bicycling. Before and immediately after exercise, blood of the participants was taken to evaluate oxidative stress markers. The results found that none of the parameters were statistically different before either MICE or MIIE exercises; NO (1.86 ± 0.68 and 1.76 ± 0.59 µmol/L), MDA (1.89 ± 0.59 and 1.81 ± 0.53 µmol/L), GSH (2.86 ± 0.65 and 2.75 ± 0.64 mmol/L). After MICE, the NO (2.53 ± 0.58 µmol/L) and MDA (2.32 ± 0.52 µmol/L) increased, whereas GSH (2.39 ± 0.52 mmol/L) decreased significantly, the same as in the MIIE results regarding MDA (2.16 ± 0.54 µmol/L) and NO (2.80 ± 0.62 µmol/L). However, the GSH result was not significantly different after finishing the MIIE (2.56 ± 0.59 mmol/L). It was noticeable that the oxidative stress parameters between exercises were not statistically different, except for the NO in MIIE compared with MICE. Therefore, it can be concluded that MIIE in this preliminary study induces more release of NO and involves less antioxidant GSH when compared with MICE.