Please use this identifier to cite or link to this item: http://cmuir.cmu.ac.th/jspui/handle/6653943832/76952
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dc.contributor.authorSuree Yoowannakulen_US
dc.contributor.authorSurachet Vongsanimen_US
dc.contributor.authorKamonwan Tangvoraphonkchaien_US
dc.contributor.authorAhmed Mohameden_US
dc.contributor.authorAndrew Davenporten_US
dc.date.accessioned2022-10-16T07:20:43Z-
dc.date.available2022-10-16T07:20:43Z-
dc.date.issued2021-12-01en_US
dc.identifier.issn20591381en_US
dc.identifier.other2-s2.0-85100152210en_US
dc.identifier.other10.1186/s41100-021-00321-3en_US
dc.identifier.urihttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85100152210&origin=inwarden_US
dc.identifier.urihttp://cmuir.cmu.ac.th/jspui/handle/6653943832/76952-
dc.description.abstractBackground: Quality of life for haemodialysis (HD) patients may be affected by symptoms during dialysis treatments, and patient groups have highlighted the need to improve post-dialysis fatigue and dialysis-related symptoms. As changes in extracellular water (ECW) may lead to cramps and other symptoms, we wished to determine whether there was an association between ECW and intra-dialytic symptoms. Methods: We reviewed the hospital records of HD patients who completed a self-reported intra-dialytic symptom questionnaire, using a visual analogue scale, who had contemporaneous pre- and postdialysis bioimpedance ECW measurements adjusted to height (aECW). Results: We studied dialysis sessions of 506 patients, 314 (62.1%) male, 226 (44.7%) diabetic, mean age 64.6 ± 15.7 years, weight 69.9 ± 17.4 kg, and duration of dialysis treatment 26 (9.6–60.1) months. We divided patients into three groups according to pre-dialysis aECW, and total dialysis symptom scores were greater for those in the lower tertile (25 (10–41) vs middle 18 (8.5–34) vs upper 20 (7–31), p < 0.05). Only feeling cold, dizziness, and low blood pressure were statistically different between the three pre-dialysis aECW groups, and there was no difference in post-dialysis recovery times. We analysed the effect of the fall in aECW pre-to post-dialysis. Patients in the group with the greatest fall in aECW did not report more intra-dialytic symptoms or longer recovery times. Conclusion: We found that patients starting dialysis with lower relative ECW were more likely to report intra-dialytic symptoms than those with greater amounts of fluid to remove, and most commonly reported symptoms were associated with intra-vascular volume depletion.en_US
dc.subjectMedicineen_US
dc.titlePatient-reported symptoms during dialysis: the effect of pre-dialysis extracellular water and change in extracellular water post-dialysisen_US
dc.typeJournalen_US
article.title.sourcetitleRenal Replacement Therapyen_US
article.volume7en_US
article.stream.affiliationsThe Royal Free Hospitalen_US
article.stream.affiliationsBhumibol Adulyadej Hospitalen_US
article.stream.affiliationsMahasarakham Universityen_US
article.stream.affiliationsChiang Mai Universityen_US
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