Synthesis, Characterization and Biological Applications of Mo(VI) and V(IV) Complexes of 2-[2-(2-aminoethoxy)ethoxy]ethanamine dithiocarbamate

Abstract

New dithiocarbamate (DTC) 2-[2-(2-aminoethoxy) ethoxy] ethanamine dithiocarbamate (AEEEA DTC) ligand (L) was synthesized by the reaction of diamine and carbon disulfide with 1:2 molar ratio. Molybdenum (VI) and vanadium (IV) complexes of this ligand, ([MoO2L] and [VOL]) were prepared by 1:1 molar proportion. Prepared ligand and complexes were characterized using molar conductance, elemental analysis, UV- visible, FT-IR and 1H-NMR spectroscopy. In the FT-IR spectra, band for S-H of the ligand disappeared in the complex confirming the sulphur-metal(S-M) linkage. The presence of peak for S-H proton in the 1H-NMR spectrum of ligand and it’s disappearance in the complex supported the FT-IR result. Low molar conductivity indicated the non-electrolytic nature of the complexes. The electronic spectra and effective magnetic moment of the prepared complexes revealed the +4 and +6 oxidation state of vanadium and molybdenum, respectively. Antimicrobial activities were investigated for the synthesized ligand. AEEEA DTC exhibited antibacterial behavior against all of the tested bacteria and inhibited Bacillus cereus more effectively. In the case of antifungal screening, no notable inhibition was observed.