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dc.contributor.authorSongyot Anuchapreedaen_US
dc.contributor.authorRiki Anzawaen_US
dc.contributor.authorNatsima Viriyaadhammaaen_US
dc.contributor.authorWaranya Neimkhumen_US
dc.contributor.authorWantida Chaiyanaen_US
dc.contributor.authorSiriporn Okonogien_US
dc.contributor.authorToyonobu Usukien_US
dc.description.abstractCopyright © 2020 Elsevier Ltd. All rights reserved. The leaves of the kaffir lime (Citrus hystrix) are commonly used in cuisine and folk medicine. The aim of this study was to isolate a bioactive compound in kaffir lime leaves and characterize its biological activity. The compound was isolated from a hexane fractional extract and identified as agrostophillinol. This is the first report of agrostophillinol isolated from kaffir lime leaves. In terms of cytotoxicity, agrostophillinol exhibited IC50 values of 36.27 ± 7.30 and 53.44 ± 10.63 μg/mL against EoL-1 and HL60 cells, respectively. Agrostophillinol also exhibited potent anti-inflammatory activity, significantly inhibiting IL-6 secretion.en_US
dc.subjectBiochemistry, Genetics and Molecular Biologyen_US
dc.subjectPharmacology, Toxicology and Pharmaceuticsen_US
dc.titleIsolation and biological activity of agrostophillinol from kaffir lime (Citrus hystrix) leavesen_US
article.title.sourcetitleBioorganic & medicinal chemistry lettersen_US
article.volume30en_US Chalermprakiet Universityen_US Universityen_US Mai Universityen_US
Appears in Collections:CMUL: Journal Articles

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