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dc.contributor.authorMarcus R. Keogh-Brownen_US
dc.contributor.authorHenning Tarp Jensenen_US
dc.contributor.authorSanjay Basuen_US
dc.contributor.authorWichai Aekplakornen_US
dc.contributor.authorSoledad Cuevasen_US
dc.contributor.authorAlan D. Dangouren_US
dc.contributor.authorShabbir H. Gheewalaen_US
dc.contributor.authorRosemary Greenen_US
dc.contributor.authorEdward J.M. Joyen_US
dc.contributor.authorNipa Rojroongwasinkulen_US
dc.contributor.authorNalitra Thaipraserten_US
dc.contributor.authorBhavani Shankaren_US
dc.contributor.authorRichard D. Smithen_US
dc.date.accessioned2019-09-16T12:56:08Z-
dc.date.available2019-09-16T12:56:08Z-
dc.date.issued2019-08-16en_US
dc.identifier.issn14787954en_US
dc.identifier.other2-s2.0-85070906012en_US
dc.identifier.other10.1186/s12963-019-0191-yen_US
dc.identifier.urihttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85070906012&origin=inwarden_US
dc.identifier.urihttp://cmuir.cmu.ac.th/jspui/handle/6653943832/66712-
dc.description.abstract© 2019 The Author(s). Background: Palm oil's high yields, consequent low cost and highly versatile properties as a cooking oil and food ingredient have resulted in its thorough infiltration of the food sector in some countries. Longitudinal studies have associated palm oil's high saturated fatty acid content with non-communicable disease, but neither the economic or disease burdens have been assessed previously. Methods: This novel palm oil-focussed disease burden assessment employs a fully integrated health, macroeconomic and demographic Computable General Equilibrium Model for Thailand with nine regional (urban/rural) households. Nutritional changes from food consumption are endogenously translated into health (myocardial infarction (MI) and stroke) and population outcomes and are fed back into the macroeconomic model as health and caregiver-related productive labour supply effects and healthcare costs to generate holistic 2016-2035 burden estimates. Model scenarios mirror the replacement of palm cooking oil with other dietary oils and are compared with simulated total Thai health and macroeconomic burdens for MI and stroke. Results: Replacing consumption of palm cooking oil with other dietary oils could reduce MI/stroke incident cases by 8280/2639 and cumulative deaths by 4683/894 over 20 years, removing approximately 0.5% of the total Thai burden of MI/stroke. This palm cooking oil replacement would reduce consumption shares of saturated/monounsaturated fatty acids in Thai household consumption by 6.5%/3% and increase polyunsaturated fatty acid consumption shares by 14%, yielding a 1.74% decrease in the population-wide total-to-HDL cholesterol ratio after 20 years. The macroeconomic burden that would be removed is US$308mn, approximately 0.44% of the total burden of MI/stroke on Thailand's economy or 0.003% of cumulative 20-year GDP. Bangkok and Central region households benefit most from removal of disease burdens. Conclusions: Simulations indicate that consumption of palm cooking oil, rather than other dietary oils, imposes a negative health burden (MI and stroke) and associated economic burden on a high consuming country, such as Thailand. Integrated sectoral model frameworks to assess these burdens are possible, and burden estimates from our simulated direct replacement of palm cooking oil indicate that using these frameworks both for broader analyses of dietary palm oil use and total burden analyses of other diseases may also be beneficial.en_US
dc.subjectMedicineen_US
dc.titleEvidence on the magnitude of the economic, health and population effects of palm cooking oil consumption: An integrated modelling approach with Thailand as a case studyen_US
dc.typeJournalen_US
article.title.sourcetitlePopulation Health Metricsen_US
article.volume17en_US
article.stream.affiliationsSOAS University of Londonen_US
article.stream.affiliationsLondon School of Hygiene & Tropical Medicineen_US
article.stream.affiliationsKøbenhavns Universiteten_US
article.stream.affiliationsUniversity of Exeteren_US
article.stream.affiliationsFaculty of Medicine, Ramathibodi Hospital, Mahidol Universityen_US
article.stream.affiliationsStanford Universityen_US
article.stream.affiliationsKing Mongkut s University of Technology Thonburien_US
article.stream.affiliationsChiang Mai Universityen_US
article.stream.affiliationsInstitute of Nutritionen_US
article.stream.affiliationsFaculty of Epidemiology and Population Healthen_US
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