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dc.contributor.authorP. Thopanen_US
dc.contributor.authorT. Sekien_US
dc.contributor.authorL. D. Yuen_US
dc.contributor.authorU. Tippawanen_US
dc.contributor.authorJ. Matsuoen_US
dc.date.accessioned2019-08-05T04:43:15Z-
dc.date.available2019-08-05T04:43:15Z-
dc.date.issued2019-06-01en_US
dc.identifier.issn0168583Xen_US
dc.identifier.other2-s2.0-85063762942en_US
dc.identifier.other10.1016/j.nimb.2019.04.001en_US
dc.identifier.urihttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85063762942&origin=inwarden_US
dc.identifier.urihttp://cmuir.cmu.ac.th/jspui/handle/6653943832/65872-
dc.description.abstract© 2019 Elsevier B.V. Cluster ion beam effect on large biomolecules is interesting due to differences in ion beam characters from normal ion beams and applications in analysis of the molecules as the cluster ion beam should be more effective in fragmenting large and complicated biomolecules to make study of the complex molecular structure possible. Argon gas cluster ion beam (Ar-GCIB) at 10 keV bombarded samples of DSPC (1,2-distearoyl-sn-glycero-3-phosphocholine, C 44 H 88 NO 8 P, monoisotopic molecular weight 789.6 Da), angiotensin II (C 50 H 71 N 13 O 12 , monoisotopic molecular weight 1045.5 Da) and leucine enkephalin (C 28 H 37 N 5 O 7 , monoisotopic molecular weight 555.6 Da). The bombardment-generated fragments were in-situ analyzed and measured using the tandem quadrupole – time-of-flight secondary ion mass spectrometry (Q-ToF-SIMS) technique. The experiment was operated within an integrated system of Ar-GCIB and Q-ToF-SIMS. Two modes, i.e. MS (quadruple off) and MS/MS (quadrupole on), were applied in the ToF-SIMS measurement. Particularly, the secondary ion fragmentation with the collision energy dependence was focused in the study.en_US
dc.subjectPhysics and Astronomyen_US
dc.titleCluster ion beam bombardment and Q-ToF-SIMS analysis of large biomoleculesen_US
dc.typeJournalen_US
article.title.sourcetitleNuclear Instruments and Methods in Physics Research, Section B: Beam Interactions with Materials and Atomsen_US
article.volume448en_US
article.stream.affiliationsRajamangala University of Technology Isanen_US
article.stream.affiliationsJapan Science and Technology Agencyen_US
article.stream.affiliationsKyoto Universityen_US
article.stream.affiliationsChiang Mai Universityen_US
article.stream.affiliationsCommission on Higher Educationen_US
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