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dc.contributor.authorSoranun Chantarangsuen_US
dc.contributor.authorTim Cresseyen_US
dc.contributor.authorSurakameth Mahasirimongkolen_US
dc.contributor.authorYardpiroon Tawonen_US
dc.contributor.authorNicole Ngo-Giang-Huongen_US
dc.contributor.authorGonzague Jourdainen_US
dc.contributor.authorMarc Lallemanten_US
dc.contributor.authorWasun Chantratitaen_US
dc.description.abstractUnderstanding genetically encoded inherited differences in drug metabolism and drug targets offers the promise of minimizing adverse drug reactions and improving therapies. We have compared two real-time PCR-based methods, the TaqMan®and LightCycler™ for the pharmacogenetic evaluation of CYP2B6 516G>T polymorphism. Both methods were found to be suitable for pharmacogenetic testing of CYP2B6 516G>T in the meaning of time consumption, accurate genotype calling, flexible reaction format, simple data analysis, and low cost per assay. The genotype success rate was similar, but the LightCycler procedure was less expensive in terms of cost per sample and shorter running time. © 2007 Elsevier Ltd. All rights reserved.en_US
dc.subjectBiochemistry, Genetics and Molecular Biologyen_US
dc.titleComparison of the TaqMan and LightCycler systems in evaluation of CYP2B6 516G>T polymorphismen_US
article.title.sourcetitleMolecular and Cellular Probesen_US
article.volume21en_US of Medicine, Thammasat Universityen_US Mai Universityen_US Ministry of Public Healthen_US
Appears in Collections:CMUL: Journal Articles

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