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dc.contributor.authorHideaki Shimizuen_US
dc.contributor.authorTung Gia Phanen_US
dc.contributor.authorShuichi Nishimuraen_US
dc.contributor.authorShoko Okitsuen_US
dc.contributor.authorNiwat Maneekarnen_US
dc.contributor.authorHiroshi Ushijimaen_US
dc.description.abstractA total of 337 fecal specimens were collected from infants and children with acute gastroenteritis in Maizuru City, Japan from July 2004 to June 2005 and tested for the presence of rotavirus, norovirus, sapovirus, astrovirus, and adenovirus by RT-multiplex PCR. Among diarrheal viruses detected, norovirus was the most prevalent (13.6%, 46 of 337), followed by adenovirus (8%, 27 of 337), group A rotavirus (5%, 17 of 337), astrovirus (1.8%, 6 of 337), and sapovirus (1.8%, 6 of 337), respectively. Adenovirus was subjected to molecular genetic analysis by sequencing. Adenovirus detected in this study was classified into five serotypes, namely Ad1, Ad2, Ad3, Ad5, and Ad41. Of these, Ad41 was the most predominant serotype that accounted for 85.2% (23 of 27). It was noteworthy to point out that Ad41 infection was apparently confined only to the period of 4 months (October 2004 through January 2005). This pattern of infection implied the outbreak of Ad41 in these subjects, which was the first outbreak of acute gastroenteritis attributed to adenovirus in Maizuru City, Japan. Another interesting feature of the study was the existence of two Ad41 subtypes co-circulating in this outbreak. This report confirmed the presence of adenovirus as one of an important cause of acute gastroenteritis among Japanese infants and children. © 2006 Elsevier B.V. All rights reserved.en_US
dc.subjectAgricultural and Biological Sciencesen_US
dc.subjectBiochemistry, Genetics and Molecular Biologyen_US
dc.subjectImmunology and Microbiologyen_US
dc.titleAn outbreak of adenovirus serotype 41 infection in infants and children with acute gastroenteritis in Maizuru City, Japanen_US
article.title.sourcetitleInfection, Genetics and Evolutionen_US
article.volume7en_US of International Healthen_US Mai Universityen_US
Appears in Collections:CMUL: Journal Articles

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