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dc.contributor.authorChatchada Wuttikulen_US
dc.contributor.authorToshiaki Taokaen_US
dc.contributor.authorToshiaki Akashien_US
dc.contributor.authorHiroyuki Nakagawaen_US
dc.contributor.authorToshiteru Miyasakaen_US
dc.contributor.authorMasahiko Sakamotoen_US
dc.contributor.authorKatsutoshi Takayamaen_US
dc.contributor.authorTakeshi Wadaen_US
dc.contributor.authorSatoru Kitanoen_US
dc.contributor.authorJunko Takahamaen_US
dc.contributor.authorNagaaki Marugamien_US
dc.contributor.authorKimihiko Kichikawaen_US
dc.description.abstractPurpose: This study discusses prominent signal intensity of T1/T2 prolongation of subcortical white matter within the anterior temporal region in premature infant brains that radiologists may encounter when interpreting conventional screening MRIs. Materials and Methods: T1- and T2-weighted images of 69 preterm and term infants with no neurological abnormalities or developmental delays were evaluated retrospectively for areas of prominent signal intensity of T1/T2 prolongation in white matter. We measured signal intensities of anterior temporal white matter, deep temporal white matter, frontopolar white matter and subcortical white matter of the precentral gyrus. We accessed chronological changes in signal intensity in the anterior and deep temporal white matter. We also analyzed variance tests among the signal intensity ratios to the ipsilateral thalamus of white matter areas by gestational age. Results: There was high frequency of prominent signal intensity of T1/T2 prolongation in the temporal tip, particularly at a gestational age of 36-38 weeks. Signal intensity ratio of the anterior temporal white matter was lower on T1-weighted images and higher on T2-weighted images, and the finding became less prominent with increasing gestational age. The signal intensity ratios of anterior temporal white matter at a gestational age of 36-37 weeks and 38-39 weeks were significantly different from other regions. Conclusion: Prominent signal intensity of T1/T2 prolongation of subcortical white matter of the anterior temporal region is seen in normal premature infants, especially those at 36-39 gestational weeks. Although it is a prominent finding, radiologists should understand that these findings do not represent a pathological condition. © 2008 Elsevier Inc. All rights reserved.en_US
dc.subjectBiochemistry, Genetics and Molecular Biologyen_US
dc.titleProminent signal intensity of T1/T2 prolongation in subcortical white matter of the anterior temporal region on conventional screening MRI of late preterm infants with normal developmenten_US
article.title.sourcetitleMagnetic Resonance Imagingen_US
article.volume26en_US Medical Universityen_US Mai Universityen_US
Appears in Collections:CMUL: Journal Articles

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