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dc.contributor.authorPimwalan Techaikoolen_US
dc.contributor.authorDonraporn Daranarongen_US
dc.contributor.authorJutamas Kongsuken_US
dc.contributor.authorDheerawan Boonyawanen_US
dc.contributor.authorNursyuhada Haronen_US
dc.contributor.authorWilliam S. Harleyen_US
dc.contributor.authorKyle A. Thomsonen_US
dc.contributor.authorL. John R. Fosteren_US
dc.contributor.authorWinita Punyodomen_US
dc.description.abstract© 2017 Society of Chemical Industry Poly[(l-lactide)-co-(ϵ-caprolactone)] (PLCL) and poly[(l-lactide)-co-glycolide] (PLGA) copolymers are widely used in neural guide tissue regeneration. In this research, the surface modification of their hydrophilicity was achieved using plasma treatment. Attachment and proliferation of olfactory ensheathing cells on treated electrospun membranes increased by 26 and 32%, respectively, compared to the untreated PLCL and PLGA counterparts. Cells cultivated on both the PLCL and PLGA membranes showed high viability (>95%) and healthy morphologies with no evidence of cytotoxic effects. Cells grown on treated electrospun fibres displayed significant increases in mitochondrial activity and reductions in membrane leakage when compared to untreated samples. The results suggested that plasma treatment of the surface of the polymers enhanced both cell viability and growth without incurring any cytotoxic effects. © 2017 Society of Chemical Industry.en_US
dc.subjectMaterials Scienceen_US
dc.titleEffects of plasma treatment on biocompatibility of poly[(L-lactide)-co-(ϵ-caprolactone)] and poly[(L-lactide)-co-glycolide] electrospun nanofibrous membranesen_US
article.title.sourcetitlePolymer Internationalen_US
article.volume66en_US Mai Universityen_US of New South Wales (UNSW) Australiaen_US Sight Instituteen_US
Appears in Collections:CMUL: Journal Articles

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