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Title: การศึกษาเศษอาหารในลำไส้เล็กส่วนต้นเพื่อเป็นวิธีเสริมในการตรวจทางพิษวิทยา
Other Titles: The Study of Duodenal Content for an Enhance Examination in Toxicology
Authors: จาตุรงค์ กันชัย
วชิราภรณ์ โปธา
Keywords: เศษอาหาร
Issue Date: 2557
Publisher: เชียงใหม่ : บัณฑิตวิทยาลัย มหาวิทยาลัยเชียงใหม่
Abstract: The objective of this study was usingduodenal contentas an alternative or an enhance specimen in toxicology instead of gastric content. The samples werecollected from 30 corpseswhich died fromunknown cause with history of toxic substances or drug exposure. The samples were extracted with acids and bases and then analyzed byliquidchromatography - mass spectrometry (LC-MS-MS). The results werecompared duodenal content with gastric contentusingblood and urineas gold standards. Toxic substances or drugswere found in 25 cases (83.30%).The sensitivity, specificity and accuracy of the duodenal content versus the gastric content which were calculated and compared with blood were76.67:80.00, 41.67:25.00, 70.83:70.83andurine were68.29:73.17, 27.27:18.18 and 59.62: 61.54 respectively. Statistic analysis usingChi-square showedthat there was no significantdifference between duodenal and gastric content (p>0.05). Then, the duodenal content can be used as an alternative specimen for toxicologydiagnosis.
Appears in Collections:GRAD-Sciences and Technology: Independent Study (IS)

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ABSTRACT.pdfABSTRACT197.19 kBAdobe PDFView/Open
APPENDIX.pdfAPPENDIX929.5 kBAdobe PDFView/Open
CHAPTER 1.pdfCHAPTER 1281.11 kBAdobe PDFView/Open
CHAPTER 2.pdfCHAPTER 2186.56 kBAdobe PDFView/Open
CHAPTER 3.pdfCHAPTER 3280.74 kBAdobe PDFView/Open
CHAPTER 4.pdfCHAPTER 4263.28 kBAdobe PDFView/Open
CHAPTER 5.pdfCHAPTER 5188.97 kBAdobe PDFView/Open
CONTENT.pdfCONTENT242.49 kBAdobe PDFView/Open
COVER.pdfCOVER662.27 kBAdobe PDFView/Open

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