Please use this identifier to cite or link to this item: http://cmuir.cmu.ac.th/jspui/handle/6653943832/61512
Title: The influence of pH on the G-quadruplex binding selectivity of perylene derivatives
Authors: Wirote Tuntiwechapikul
Thanachai Taka
Mathilde Béthencourt
Luksana Makonkawkeyoon
T. Randall Lee
Keywords: Biochemistry, Genetics and Molecular Biology
Chemistry
Pharmacology, Toxicology and Pharmaceutics
Issue Date: 1-Aug-2006
Abstract: Three new perylene derivatives with branched ionizable side chains were synthesized, and their G-quadruplex binding specificities were compared by spectroscopic and electrophoretic analysis with two well-studied G-quadruplex ligands: PIPER and TmPyP4. The value of pH and consequent charge formation and self-aggregation of these perylene derivatives influences not only the type of G-quadruplex formation, but also the G-quadruplex binding selectivity. © 2006 Elsevier Ltd. All rights reserved.
URI: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=33745141952&origin=inward
http://cmuir.cmu.ac.th/jspui/handle/6653943832/61512
ISSN: 0960894X
Appears in Collections:CMUL: Journal Articles

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