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Title: Ph<inf>3</inf>P/I<inf>2</inf>-Mediated Synthesis of 3-Aryl-Substituted and 3,4-Disubstituted Coumarins
Authors: Wong Phakhodee
Chuthamat Duangkamol
Dolnapa Yamano
Mookda Pattarawarapan
Keywords: Chemistry
Issue Date: 21-Apr-2017
Abstract: © Georg Thieme Verlag Stuttgart New York. Ph3P/I2-Et3N-mediated one-pot two-step esterification-cyclization toward 3-aryl coumarins and 3-aryl-4-methylcoumarins is reported. The reaction of a variety of aryl acetic acids containing steric or reactive group with 2-hydroxybenzaldehydes or 2′-hydroxyacetophenone proceeded smoothly at room temperature to afford the corresponding products in good to excellent yields using inexpensive and readily available reactants and reagents.
ISSN: 14372096
Appears in Collections:CMUL: Journal Articles

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