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|Title:||A convenient synthesis of 4-arylidene-2-phenyl-5(4H)-oxazolones under solvent-assisted grinding|
|Keywords:||Biochemistry, Genetics and Molecular Biology|
Pharmacology, Toxicology and Pharmaceutics
|Abstract:||© 2016 Elsevier Ltd A facile and effective approach for the synthesis of 4-arylidene-2-phenyl-5(4H)-oxazolones has been developed. Under solvent-assisted grinding in the presence of 2,4,6-trichloro-1,3,5-triazine, catalytic triphenylphosphine, and sodium carbonate, dehydration–condensation of hippuric acid with aromatic aldehydes proceeded rapidly within minutes at room temperature to afford the products in good to excellent yields.|
|Appears in Collections:||CMUL: Journal Articles|
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