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Title: A new cytotoxic clerodane diterpene from casearia graveolens twigs
Authors: Pornphimol Meesakul
Thunwadee Ritthiwigrom
Sarot Cheenpracha
Tawanun Sripisut
Wisanu Maneerat
Theeraphan MacHan
Surat Laphookhieo
Keywords: Agricultural and Biological Sciences
Pharmacology, Toxicology and Pharmaceutics
Issue Date: 23-Jan-2016
Abstract: The first phytochemical investigation of Casearia graveolens twigs led to the isolation and identification of a new clerodane diterpene, caseariagraveolin (1), together with six known compounds (2-7). Their structures were elucidated by intensive analysis of their spectroscopic data. Compound 1 showed strong cytotoxicity against oral cavity and breast cancer cell lines with IC50 values of 2.48 and 6.63 ìM, respectively.
ISSN: 15559475
Appears in Collections:CMUL: Journal Articles

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