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Title: | A new cytotoxic clerodane diterpene from casearia graveolens twigs |
Authors: | Pornphimol Meesakul Thunwadee Ritthiwigrom Sarot Cheenpracha Tawanun Sripisut Wisanu Maneerat Theeraphan MacHan Surat Laphookhieo |
Authors: | Pornphimol Meesakul Thunwadee Ritthiwigrom Sarot Cheenpracha Tawanun Sripisut Wisanu Maneerat Theeraphan MacHan Surat Laphookhieo |
Keywords: | Agricultural and Biological Sciences;Medicine;Pharmacology, Toxicology and Pharmaceutics |
Issue Date: | 23-Jan-2016 |
Abstract: | The first phytochemical investigation of Casearia graveolens twigs led to the isolation and identification of a new clerodane diterpene, caseariagraveolin (1), together with six known compounds (2-7). Their structures were elucidated by intensive analysis of their spectroscopic data. Compound 1 showed strong cytotoxicity against oral cavity and breast cancer cell lines with IC50 values of 2.48 and 6.63 ìM, respectively. |
URI: | https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84973408865&origin=inward http://cmuir.cmu.ac.th/jspui/handle/6653943832/55050 |
ISSN: | 15559475 1934578X |
Appears in Collections: | CMUL: Journal Articles |
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