Weight as predictors of clinical progression and treatment failure: Results from the TREAT Asia Pediatric HIV observational database

Azar Kariminia; Nicolas Durier; Gonzague Jourdain; Suneeta Saghayam; Chau V. Do; Lam Van Nguyen; Rawiwan Hansudewechakul; Pagakrong Lumbiganon; Kulkanya Chokephaibulkit; Khanh Huu Truong; Virat Sirisanthana; Vibol Ung; Saphonn Vonthanak; Jintanat Ananworanich; Nik Khairulddin Nik Yusoff; Nia Kurniati; Kamarul Azahar Razali; Moy Siew Fong; Revathy Nallusamy; Dewi Kumara Wati

Please use this identifier to cite or link to this item: http://cmuir.cmu.ac.th/jspui/handle/6653943832/53714

Title:	Weight as predictors of clinical progression and treatment failure: Results from the TREAT Asia Pediatric HIV observational database
Authors:	Azar Kariminia Nicolas Durier Gonzague Jourdain Suneeta Saghayam Chau V. Do Lam Van Nguyen Rawiwan Hansudewechakul Pagakrong Lumbiganon Kulkanya Chokephaibulkit Khanh Huu Truong Virat Sirisanthana Vibol Ung Saphonn Vonthanak Jintanat Ananworanich Nik Khairulddin Nik Yusoff Nia Kurniati Kamarul Azahar Razali Moy Siew Fong Revathy Nallusamy Dewi Kumara Wati
Authors:	Azar Kariminia Nicolas Durier Gonzague Jourdain Suneeta Saghayam Chau V. Do Lam Van Nguyen Rawiwan Hansudewechakul Pagakrong Lumbiganon Kulkanya Chokephaibulkit Khanh Huu Truong Virat Sirisanthana Vibol Ung Saphonn Vonthanak Jintanat Ananworanich Nik Khairulddin Nik Yusoff Nia Kurniati Kamarul Azahar Razali Moy Siew Fong Revathy Nallusamy Dewi Kumara Wati
Keywords:	Medicine
Issue Date:	1-Sep-2014
Abstract:	Objective: To evaluate the value of time-updated weight and height in predicting clinical progression, and immunological and virological failure in children receiving combination antiretroviral therapy (cART). Methods: We used Cox regression to analyze data of a cohort of Asian children. Results: A total of 2608 children were included; median age at cART was 5.7 years. Time-updated weight for age z score <-3 was associated with mortality (P < 0.001) independent of CD4% and <-2 was associated with immunological failure (P ≤ 0.03) independent of age at cART. Conclusions: Weight monitoring provides useful data to inform clinical management of children on cART in resource-limited settings. © 2014 by Lippincott Williams & Wilkins.
URI:	https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84906085101&origin=inward http://cmuir.cmu.ac.th/jspui/handle/6653943832/53714
ISSN:	10779450 15254135
Appears in Collections:	CMUL: Journal Articles

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