Please use this identifier to cite or link to this item: http://cmuir.cmu.ac.th/jspui/handle/6653943832/53714
Title: Weight as predictors of clinical progression and treatment failure: Results from the TREAT Asia Pediatric HIV observational database
Authors: Azar Kariminia
Nicolas Durier
Gonzague Jourdain
Suneeta Saghayam
Chau V. Do
Lam Van Nguyen
Rawiwan Hansudewechakul
Pagakrong Lumbiganon
Kulkanya Chokephaibulkit
Khanh Huu Truong
Virat Sirisanthana
Vibol Ung
Saphonn Vonthanak
Jintanat Ananworanich
Nik Khairulddin Nik Yusoff
Nia Kurniati
Kamarul Azahar Razali
Moy Siew Fong
Revathy Nallusamy
Dewi Kumara Wati
Keywords: Medicine
Issue Date: 1-Sep-2014
Abstract: Objective: To evaluate the value of time-updated weight and height in predicting clinical progression, and immunological and virological failure in children receiving combination antiretroviral therapy (cART). Methods: We used Cox regression to analyze data of a cohort of Asian children. Results: A total of 2608 children were included; median age at cART was 5.7 years. Time-updated weight for age z score <-3 was associated with mortality (P < 0.001) independent of CD4% and <-2 was associated with immunological failure (P ≤ 0.03) independent of age at cART. Conclusions: Weight monitoring provides useful data to inform clinical management of children on cART in resource-limited settings. © 2014 by Lippincott Williams & Wilkins.
URI: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84906085101&origin=inward
http://cmuir.cmu.ac.th/jspui/handle/6653943832/53714
ISSN: 10779450
15254135
Appears in Collections:CMUL: Journal Articles

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