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|Title:||Phenylpropanoid derivatives from Clausena harmandiana fruits|
|Keywords:||Agricultural and Biological Sciences|
Biochemistry, Genetics and Molecular Biology
|Abstract:||A new phenylpropanoid derivative, harmandianone (1), along with four known compounds: verimol B (2), (E)-3-(2-hydroxy-4-methoxy-phenyl)propanoate (3), (E)-methyl p-coumarate (4), and (E)-5-methoxy-2-(prop-1-enyl)phenol (5) was isolated from the acetone extract of Clausena harmandiana fruits. All structures were characterized by spectroscopic methods (UV, IR, NMR and ESI-TOF-MS). Compounds 1 and 3-5 demonstrated weak antibacterial activity against Escherichia coli TISTR 780, methicillin-resistant Staphylococcus aureus SK1, Salmonella typhimurium TISTR 292 and S. aureus TISTR1466, with MIC values between 64 and 128 μg/mL.Copyright © 2012 Phytochemical Society of Europe. Published by Elsevier B.V. All rights reserved.|
|Appears in Collections:||CMUL: Journal Articles|
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