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dc.contributor.authorSupaporn Kradtap Hartwellen_US
dc.contributor.authorBoonraksa Srisawangen_US
dc.contributor.authorPrachya Kongtawelerten_US
dc.contributor.authorGary D. Christianen_US
dc.contributor.authorKate Grudpanen_US
dc.description.abstractThalassemia involves gene mutation that causes the production of an insufficient amount of normal structure globin chains while Hb variant involves gene mutation that causes the change in type or number of amino acid of the globin chain. It has been reported that some 200 million people worldwide had hemoglobinopathies of some sort. Attempts to develop effective and economical techniques for screening and analysis of thalassemia and Hb variants have become very important. In this review, we report the different techniques available, ranging from initial screening to extensive analysis, comparing advantages and disadvantages. Some indirect studies related to thalassemia indication and treatment follow-up are also included. We hope that information on these various techniques would be useful for some scientists who are working on development of a new technique or improving the existing ones. © 2004 Elsevier B.V. All rights reserved.en_US
dc.titleReview on screening and analysis techniques for hemoglobin variants and thalassemiaen_US
article.volume65en_US Mai Universityen_US of Washington, Seattleen_US
Appears in Collections:CMUL: Journal Articles

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