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http://cmuir.cmu.ac.th/jspui/handle/6653943832/75201| Title: | Macluracochinones A-E, antimicrobial flavonoids from Maclura cochinchinensis (Lour.) Corner |
| Authors: | Isaraporn Polbuppha Virayu Suthiphasilp Tharakorn Maneerat Rawiwan Charoensup Thunwadee Limtharakul Sarot Cheenpracha Stephen G. Pyne Surat Laphookhieo |
| Authors: | Isaraporn Polbuppha Virayu Suthiphasilp Tharakorn Maneerat Rawiwan Charoensup Thunwadee Limtharakul Sarot Cheenpracha Stephen G. Pyne Surat Laphookhieo |
| Keywords: | Agricultural and Biological Sciences;Biochemistry, Genetics and Molecular Biology |
| Issue Date: | 1-Jul-2021 |
| Abstract: | The phytochemical investigation of the fruit and leaf extracts of Maclura cochinchinensis (Lour.) Corner (Moraceae) resulted in the isolation and identification of four undescribed isoflavones (macluracochinones A-D) and one undescribed flavone (macluracochinone E), together with 24 known compounds. The structures of the undescribed compounds were elucidated using nuclear magnetic resonance (NMR) and high-resolution electrospray ionization time-of-flight mass spectrometry (HRESITOFMS) experiments. Gancaonin M, lupiwighteone, lupalbigenin, warangalone, auriculatin, and millexatin F displayed good antibacterial activities against Gram-positive bacteria with MIC values in the range of 1–8 μg/mL. Lupalbigenin showed strong activities against methicillin-resistant Staphylococcus aureus (MRSA) and S. aureus with the same MIC value of 1 μg/mL. |
| URI: | https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85104070643&origin=inward http://cmuir.cmu.ac.th/jspui/handle/6653943832/75201 |
| ISSN: | 00319422 |
| Appears in Collections: | CMUL: Journal Articles |
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