Please use this identifier to cite or link to this item: http://cmuir.cmu.ac.th/jspui/handle/6653943832/75069
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dc.contributor.authorPiranee Kaewbuten_US
dc.contributor.authorNatapong Kosachunhanunen_US
dc.contributor.authorArintaya Phrommintikulen_US
dc.contributor.authorDujrudee Chinwongen_US
dc.contributor.authorJohn J. Hallen_US
dc.contributor.authorSurarong Chinwongen_US
dc.date.accessioned2022-10-16T06:56:40Z-
dc.date.available2022-10-16T06:56:40Z-
dc.date.issued2022-09-01en_US
dc.identifier.issn22279032en_US
dc.identifier.other2-s2.0-85138503387en_US
dc.identifier.other10.3390/healthcare10091673en_US
dc.identifier.urihttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85138503387&origin=inwarden_US
dc.identifier.urihttp://cmuir.cmu.ac.th/jspui/handle/6653943832/75069-
dc.description.abstractPatients with type 2 diabetes mellitus (T2DM) can be affected by clinical inertia, leading to abysmal results. Studies on a suitable timeframe for treatment intensification remain scarce—especially outside of developed countries. This study aimed to explore the association between time to treatment intensification and diabetes-related complications. A database from a tertiary care hospital in Thailand was retrieved in order to conduct a retrospective cohort study for the years 2011–2017. This study comprised outpatients with T2DM presenting an HbA1c of ≥7.0%. Eligible patients were divided into three groups based on the time of treatment intensification: no delayed treatment intensification, treatment intensification within 6 months, and treatment intensification after 6 months. A Cox proportional hazards model was used to investigate the association between time to treatment intensification and diabetes-related complications. A total of 686 patients were included in the final analysis. During 6.5 years of median follow-up, the group with treatment intensification within 6 months was more strongly associated with diabetic nephropathy compared to the group with no delayed treatment intensification (adjusted HR 2.35; 95%CI 1.35–4.09). Our findings reveal that delaying treatment intensification by even 6 months can increase the likelihood of diabetic nephropathy compared to no delayed treatment intensification. We suggest that patients with T2DM whose blood glucose levels are outside the target range promptly receive treatment intensification.en_US
dc.subjectHealth Professionsen_US
dc.subjectMedicineen_US
dc.subjectNursingen_US
dc.titleTime to Treatment Intensification to Reduce Diabetes-Related Complications: A Post Hoc Studyen_US
dc.typeJournalen_US
article.title.sourcetitleHealthcare (Switzerland)en_US
article.volume10en_US
article.stream.affiliationsUniversity of Phayaoen_US
article.stream.affiliationsFaculty of Medicine, Chiang Mai Universityen_US
article.stream.affiliationsUNSW Medicineen_US
article.stream.affiliationsChiang Mai Universityen_US
Appears in Collections:CMUL: Journal Articles

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