Please use this identifier to cite or link to this item: http://cmuir.cmu.ac.th/jspui/handle/6653943832/74281
Title: Immunomulation effect of alginic acid and chitooligosaccharides in silver carp (Hypophthalmichthys molitrix)
Authors: Ramasamy Harikrishnan
Gunapathy Devi
Hien Van Doan
Kesinee Gatphayak
Chellam Balasundaram
Ehab El-Haroun
Mehdi Soltani
Authors: Ramasamy Harikrishnan
Gunapathy Devi
Hien Van Doan
Kesinee Gatphayak
Chellam Balasundaram
Ehab El-Haroun
Mehdi Soltani
Keywords: Agricultural and Biological Sciences;Environmental Science;Immunology and Microbiology
Issue Date: 1-Sep-2022
Abstract: Individual and combined efficacy of chitooligosaccharides (COS) and alginic acid (AA) at 1 g, 2 g, and 3 g per kg diet was assessed on growth and disease resistance in silver carp (Hypophthalmichthys molitrix) against Edwardsiella ictaluri. Growth parameters including specific growth rate (SGR), weight gain (WG), and feed conversion rate (FCR) were significant in fish fed 2 g and 3 g kg−1 of COS or AA, and fish fed combined COS + AA at 1, 2 and 3 kg−1 diet. In all groups, the survival rate (SR) was recorded 100%, except in group fed 2 g kg−1 AA diet. All the hematological and biochemical profiles significantly increased in groups fed 2 g and 3 g kg−1 of COS, AA, and COS + AA diets. Lipase and amylase enzyme activities and superoxide dismutase (SOD), malondialdehyde (MDA), glutathione peroxidase (GPx) antioxidant enzyme activities were significantly increased in fish fed 2 g and 3 g kg−1 of COS, AA, and COS + AA diet. Respiratory burst (RB), lysozyme (Lyz), reactive oxygen species (ROS) activities, and immunoglobuline (Ig) level were enhanced significantly in fish fed 2 g kg−1 of COS or COS + AA and all 3 g kg−1 diets, whereas nitric acid (NO) production and serum AP activity were improved in 2 g kg−1 COS + AA and 3 g kg−1 COS or COS + AA diets. Pro-inflammatory cytokine such as IL-8 mRNA transcriptions was significant in 2 g kg−1 COS + AA diet and all 3 g kg−1 diet. The IL-10 anti-inflammatory cytokine mRNA transcriptions were significant in 3 g kg−1 COS or COS + AA diets. This study was confirmed that H. molitrix fed with 3 g kg−1 COS or COS + AA diets were better activity when compared to other diet.
URI: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85136549050&origin=inward
http://cmuir.cmu.ac.th/jspui/handle/6653943832/74281
ISSN: 10959947
10504648
Appears in Collections:CMUL: Journal Articles

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