Please use this identifier to cite or link to this item: http://cmuir.cmu.ac.th/jspui/handle/6653943832/73315
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dc.contributor.authorTarika Thumvijiten_US
dc.contributor.authorBenjamaporn Supawaten_US
dc.contributor.authorSakornniya Wattanapongpitaken_US
dc.contributor.authorSuchart Kothanen_US
dc.contributor.authorMontree Tungjaien_US
dc.date.accessioned2022-05-27T08:38:44Z-
dc.date.available2022-05-27T08:38:44Z-
dc.date.issued2022-07-01en_US
dc.identifier.issn18729800en_US
dc.identifier.issn09698043en_US
dc.identifier.other2-s2.0-85129035906en_US
dc.identifier.other10.1016/j.apradiso.2022.110261en_US
dc.identifier.urihttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85129035906&origin=inwarden_US
dc.identifier.urihttp://cmuir.cmu.ac.th/jspui/handle/6653943832/73315-
dc.description.abstractRadioimmunoassay (RIA) is one of the most routine laboratory tests for diagnosing thyroid disease. Patients might receive iodine in the form of intravenous iodinated radiographic contrast media (IRCM) before testing of serum thyroxin (T4) or triiodothyronine (T3) concentration by RIA. The objective was to determine the effect of IRCM on T4 and T3 hormone tests in normal, hypothyroid, and hyperthyroid hormone conditions by RIA. IRCMs (0, 2.5, 5 and 10 mgI/mL) used in this study were iopromide and iodixanol. RIA was determined by commercial T4 RIA kit and T3 RIA kits. The method suggested by the manufacturer was followed. Normal, hypothyroid, and hyperthyroid hormones condition were 1.2 ng/mL, 0.2 ng/mL and 2.2 ng/mL for T3 hormone concentration and 70 ng/mL, 30 ng/mL and 140 ng/mL for T4 hormone concentration, respectively. %Bound values were compared between IRCM-incubated groups and non-incubated group. The data showed that iopromide-incubated groups did not statistically significant change %bound values of T3 and T4 hormone tests in normal, hypothyroid, and hyperthyroid conditions, compared to the non-incubated group. In the same way, %bound values of T3 and T4 hormone tests in iodixanol-incubated groups did not change at all conditions when compared to the non-incubated group. This finding suggested that iodinated radiographic contrast media was unlikely to result in significant problems with radioimmunoassay for measuring T3 and T4 thyroid hormones.en_US
dc.subjectPhysics and Astronomyen_US
dc.titleEffect of iodinated radiographic contrast media on radioimmunoassay for measuring thyroid hormonesen_US
dc.typeJournalen_US
article.title.sourcetitleApplied Radiation and Isotopesen_US
article.volume185en_US
article.stream.affiliationsChiang Mai Universityen_US
Appears in Collections:CMUL: Journal Articles

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