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dc.contributor.authorTung Phanen_US
dc.contributor.authorTomihiko Ideen_US
dc.contributor.authorSatoshi Komotoen_US
dc.contributor.authorPattara Khamrinen_US
dc.contributor.authorNgan Thi Kim Phamen_US
dc.contributor.authorShoko Okitsuen_US
dc.contributor.authorKoki Taniguchien_US
dc.contributor.authorShuichi Nishimuraen_US
dc.contributor.authorNiwat Maneekarnen_US
dc.contributor.authorSatoshi Hayakawaen_US
dc.contributor.authorHiroshi Ushijimaen_US
dc.description.abstract© 2020 Elsevier B.V. Group A rotavirus is a leading cause of severe acute gastroenteritis worldwide. In this study, the first complete coding sequences of 11 RNA segments of human group A rotavirus G12P[8] in Japan were determined by an unbiased viral metagenomics. Its genomic constellation (VP7-VP4-VP6-VP1-VP2-VP3-NSP1-NSP2-NSP3-NSP4-NSP5 genes) was identified as G12-P[8]-I1-R1-C1-M1-A1-N1-T1-E1-H1. When performing the genetic analysis, we discovered an intergenotypic recombination event in the pig group A rotavirus G12P[8] strain BUW-14-A008. The novel recombination was found between two different genotypes G12 and G3 in the VP7 gene, and P[8] and P[13] in the VP4 gene.en_US
dc.subjectAgricultural and Biological Sciencesen_US
dc.subjectBiochemistry, Genetics and Molecular Biologyen_US
dc.subjectImmunology and Microbiologyen_US
dc.titleGenomic analysis of group A rotavirus G12P[8] including a new Japanese strain revealed evidence for intergenotypic recombination in VP7 and VP4 genesen_US
article.title.sourcetitleInfection, Genetics and Evolutionen_US
article.volume87en_US Health University School of Medicineen_US Health Universityen_US of Pittsburgh Medical Centeren_US University School of Medicineen_US Mai Universityen_US Clinicen_US
Appears in Collections:CMUL: Journal Articles

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