Please use this identifier to cite or link to this item: http://cmuir.cmu.ac.th/jspui/handle/6653943832/71338
Title: Antibacterial activities of acetic acid against major and minor pathogens isolated from mastitis in dairy cows
Authors: Noppason Pangprasit
Anyaphat Srithanasuwan
Witaya Suriyasathaporn
Surachai Pikulkaew
John K. Bernard
Wasana Chaisri
Keywords: Biochemistry, Genetics and Molecular Biology
Immunology and Microbiology
Medicine
Issue Date: 1-Nov-2020
Abstract: © 2020 by the authors. Licensee MDPI, Basel, Switzerland. The present study evaluated the antimicrobial activities of acetic acid against bovine mastitis pathogens compared to lactic acid and lauric and caprylic saturated fatty acids. Eleven mastitis pathogens were isolated from sub-clinical and clinical bovine mastitis cases for the study. An initial screening of their antibacterial activities by agar well diffusion method was performed. The minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) of each acid were obtained using a microdilution method; each acid was diluted from stock solution and then were diluted with culture broth to reach concentrations ranging from 4 to 0.004% w/v. The results showed acetic acid had the highest zone of inhibition against all pathogens except Escherichia coli compared with lauric and caprylic acids. The MIC and MBC were lowest for acetic acid against both Gram-positive (except Staphylococcus chromogenes from the coagulase negative staphylococci (CNS) group) and Gram-negative pathogens, intermediate for lactic and caprylic acids and greatest for lauric acid. In conclusion, acetic acid had antimicrobial activities against most mastitis pathogens compared with other acids. Further studies are needed to optimize the formulation and concentration of acetic acid for teat-dipping agent in the future.
URI: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85096544152&origin=inward
http://cmuir.cmu.ac.th/jspui/handle/6653943832/71338
ISSN: 20760817
Appears in Collections:CMUL: Journal Articles

Files in This Item:
There are no files associated with this item.


Items in CMUIR are protected by copyright, with all rights reserved, unless otherwise indicated.